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Global differences in brain IMPase activity have not been substantiated [38], [39], although differences could be missed by sampling different populations, or if changes only occur in a small subset of cells or brain regions.
This low grade inflammation is, however, difficult to establish by conventional histology according to the Dallas criteria because the cellular infiltrates are often sparse and may be missed by sampling error.
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These patients cannot be completely reassured, however, because a cancer might have been missed by sampling error due to the focal nature of Prostate cancer (CaP) [ 3, 4].
In each of these latter two cases, a diagnosis of primary malignant GCTB was felt by the investigator to have been missed by sampling error at initial core biopsy.
3, 4 However, there are also data to suggest that an early low cerebrospinal fluid (CSF) immunoglobulin (Ig)M response may be suggestive of a poor outcome 5; thus, if the CSF IgM rise is only transient, it may be missed by single sampling.
Passive samplers typically work by accumulating and concentrating chemicals from the surrounding water over time, allowing analyses to identify temporally short concentration surges that might be missed by water grab samples, and potentially reducing analysis and sample handling costs, allowing a greater number of sites to be monitored.
Consequently, in these studies, small lesions, which are likely to be missed by other less accurate sampling strategies, are located but are deliberately left untreated.
At a "true positive rate" of 99% (which means that only 1% of the cancer samples will be missed by the screen), the "false positive rate" is 22.2% (i.e., 22.2% of the benign samples will make it through the screen) on average for Data1 (Table 1), thereby reducing the workload of the pathologist by 4.5-fold.
With respect to HIV serology, established HIV infections are detected at comparable sensitivity by the two assays, however, individuals in a very early seroconversion stage could be missed by third generation EIA [50% of samples in seroconversion (reactive EIA/indeterminate immunoblot] resulted in false-negative immunoblot results, but still showing reactive/indeterminate ELISA].
This may be explained by sampling error, as small aneuploid populations may be missed by ICDA.
We describe the reach of RDS into populations of youth who may be missed by traditional household- and school-based sampling.
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