Sentence examples for be mediated through multiple from inspiring English sources

But, the scientists wrote, "the original hypothesis was overly simplistic because the effects of diet on coronary heart disease can be mediated through multiple biological pathways other than serum total cholesterol or low-density lipoprotein cholesterol".

BM-derived cells can differentiate into various cell types in the tumor microenvironment and the anti-tumor effect of Hh blockade may be mediated through multiple players in the cancer stroma [33].

This inhibition appears to be mediated through multiple mechanisms operating at a transcriptional level.

The interplay between depression and MetS is likely to be mediated through multiple mechanisms.

This risk disparity may be mediated through multiple pathways involving differences in characteristics of the participating cyclists as well as broader contextual and environmental factors.

It is also likely that the effects of H3K4 methylation in excluding the DNA methyltransferases could be mediated through multiple mechanisms, including its capacity to act as a docking site for components of the transcription machinery (e.g. TAF3/TFIID [66]) and the H3K4 lysine methyltransferase complexes themselves [67].

The overall effect of woody vegetation on crop yields is mediated through multiple processes and shows both positive and negative effects.

We also examined the domains of Sox2 necessary to mediate its self-association, and we determined that Sox2 self-association is mediated through multiple domains.

These effects are mediated through multiple signaling pathways, including the Ras, ERK [8], the JAK/STAT [9] and the PI3K-1A and -1B pathways [10], [11].

The anti-cancer activity is mediated through multiple signaling pathways.

The cytotoxicity of romidepsin is mediated through multiple biological effects invoked by various mechanisms.