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Analysis of maternal liver at the time of fetal resorption indicates that the observed effects may be mediated through modification of the concentration of the pyridine nucleotide coenzymes.
The effect of childhood physical activity on adult MetS may also be mediated through modification of other traditional risk factors (26) rather than due to direct effects.
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Our data indicate that the apoptotic response to DNA damage is regulated through CEP-1 mediated transcriptional induction of egl-1 and ced-13, whereas other DNA damage responses such as cell cycle arrest and DNA repair, which are also found in unicellular organisms such as yeast, might instead be mediated through posttranscriptional modifications of checkpoint proteins.
There is substantial evidence for a role of dietary antioxidants in the prevention of atherogenesis and the protective effect of antioxidant nutrients may be mediated through inhibition of the oxidative modification of LDL.
First, this effect might be mediated through cardiovascular risk factor reduction, partly through a dampening effect of ethanol on platelet aggregation, or through a modification of the serum lipid profile.
Further KDR expression in preterm PE may not be mediated through DNA methylation changes but through other factors affecting gene expression such as transcription factors, mRNA stability and histone modifications.
This may be mediated through urethral hypermobility.
"Our study suggests that these processes could be mediated through accelerated cellular ageing".
They understood that pure democracy needs to be mediated through expertise.
> Many cancers involve multiple factors like environmental factors or genetic factors with impact on interlinked biological pathways and the environmental effects are mediated through epigenetic modifications.
Since unknown mechanisms are believed to repress a large number of the OLFR genes all the time in most of the cell types, it is likely that these repression mechanisms are mediated through epigenetic modifications.
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