Sentence examples for be mediated through its from inspiring English sources
Because we observed that the two anti-platelet drugs differed substantially in their ability to regulate systemic and vascular endothelial expression of netrin-1, we postulated that aspirin-mediated suppression of monocyte arterial accumulation could be mediated through its effects on netrin-1.
The persistent and high rate of cell proliferation with platelet-derived growth factor suggests that the growth stimulatory effect of transforming growth factor-β1 may be mediated through its up-regulatory effect on platelet-derived growth factor.
This is thought to be mediated through its ability to promote keratinocytes proliferation [67], enhance revascularization [68], reduce expression of tumor necrosis factor-α (TNF-α) and attenuate macrophage infiltration [69].
Expressed at very low or undetectable levels in normal tissue, the cytoprotective effects of Hsp70i appear to be mediated through its activity as a molecular chaperone allowing proper folding of mutated proteins, and by blocking cell signaling pathways that regulate OIS and apoptosis.
As a transcription factor, NF-κB's active participation in cell death is likely to be mediated through its target genes.
This suggests that the moderate SNP effect on BMI might be mediated through its effect on the visceral BMPR2 mRNA expression level.
Further analysis of miR-373 in vivo oncogenic function reveals that it is mediated through its negative regulation of TP53INP1, LATS2 and CD44.
Recent evidence suggests that EGFR may have a radioprotective effect that is mediated through its translocation to the nucleus[33], where it acts to repair DNA damage[33].
The death of David Bowie is mediated through its "relevance" to voluble strangers.
The stimulant effects of caffeine are mediated through its antagonistic properties on neuronal adenosine receptors.
The biological effects of LPA are mediated through its cell surface G-protein coupled LPA1 7 receptors.
