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The effects on breast cancer may be mediated through increasing birth weight by birth order.
It is suggested that the influence of ginseng on increased phosphorylation of TnI may be mediated through increasing Ca2+ concentrations.
The well established effect of air pollution on cardiorespiratory mortality may not be mediated through increasing the acute risk of myocardial infarction, but through another mechanism.
Although most of the effect of viral suppression on decreasing mortality is likely to be mediated through increasing CD4+ cell count, nevertheless there remained an independent effect of detectable viral load on life expectancy.
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These effects may be mediated through increased CD44 clustering and the ERK/SOX-9 signaling pathway.
Some of this effect appears to be mediated through increased expression of heat shock protein 70 with glutamine administration [ 40].
Thus, chemosensitisation by BSO appeared to be mediated through increased intracellular drug concentrations and/or protein binding.
These actions may be mediated through increased nutrient metabolism, as evidenced by the increase of cellular NAD(P H levels associated with lowered pHi.
These metabolic changes may underpin the syndrome of cachexia and may in part be mediated through increased pro-inflammatory cytokine activity.
Here we show that APPL1 expression is increased in clamped AdipoR1-overexpressing muscles; hence, some of the effects of AdipoR1 may be mediated through increased APPL1 and/or an increased level of the interaction between AdipoR1 and APPL1.
Of note, Shenassa et al. through a comprehensive review of 5 studies identified a possible link between maternal smoking and infantile colic which may be mediated through increased plasma and intestinal motilin levels [ 15].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com