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The link might also be mediated through development of depressive symptoms around puberty.
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Secondly, some of the effects of CRP may be mediated through the development of other risk factors.
The observed increased risk of liver cancer associated with excess body weight may be mediated through the development of non-alcoholic fatty liver disease (NAFLD), a chronic liver disease that occurs in non-drinkers.
The present study, demonstrates that sexual dimorphism of the development of hypertension may be mediated through miRNA-mediated mechanisms and alterations in the ACE-2 gene.
We hypothesized that effects of preterm birth can be mediated through measurable epigenomic changes throughout development.
These effects may be related to the indirect influence of these cytokines on anti-HBs development, may be mediated through the observed increased INF-gamma production or both.
The role of metabolic stress in chronic disease development may be mediated through an inability to repair cellular damage from ROS (i.e. oxidative stress) that has been worsened by mitochondrial damage and heightened by systemic inflammation.
In addition to leaf-level effects, O3 negatively impacts plant fitness and reproductive development, which can be mediated through reduced carbon allocation from source tissues and/or through direct effects on reproductive tissues [ 9, 10].
The development of BPD may be mediated through different pathways, involving diverse risk factor profiles.
Hence, the effects of TGFB1 and MMP9 polymorphisms in the development of centrilobular disease could be mediated through macrophages via interaction with cigarette smoke.
The observed associations between parental BMIs and the development of obesity in offspring may be mediated through genetic and environmental influences.
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