Sentence examples for be mediated through altered from inspiring English sources
These changes in TACE activity attenuated LPS-induced release of TNFR and TNF from monocytes, and appear to be mediated through altered upstream p38-MAPK signalling.
Many other receptors require glycosylation of their extracellular domains for functional activity; thus frc suppression of tau toxicity may be mediated through altered glycosylation of such other transmembrane proteins.
Alcohol consumption is also associated with an increased risk of breast cancer (Smith-Warner et al, 1998; Singletary and Gapstur, 2001; Chen et al, 2011), and its effect could be mediated through altered mammographic density.
In the current study, S. marcescens and K. pneumoniae also exhibited increased biofilm-forming abilities after chlorhexidine exposure, which could potentially be mediated through altered capsule formation in K. pneumoniae (64, 69) or the upregulation of efflux pumps (60).
Increased levels of IGFBP5 correlate with defects in microvascular endothelial cells in retina and kidney [ 17], and it has been proposed that these defects could be mediated through altered response of these cells to IGF1.
Hence, our findings suggested that miR-383 inhibition of FMRP is mediated through altered levels of pRb phosphorylation.
We were not able to examine the hypothesis that the disease association of the polymorphism at +1127 INS-PstI is mediated through altered insulin levels.
The presence of HNF-1α binding sites in the CRP promoter (19) suggests that the effect on CRP is mediated through altered regulation of HNF1A expression.
This indicates that CycD/Cdk4's pathological consequences are mediated through altered mitochondrial function and a concomitant increase in reactive oxygen species.
In support of this lineage shift being mediated through altered Wnt signaling, Pb and non-esterified fatty acids in MC3T3 cells increased in vitro PPAR-γ activity and inhibited β-catenin activity.
Acute genetic knockdown of BAD in the brain impaired the glucagon response to systemic glucoprivation in mice, although whether this was mediated through altered brain GK activity remains unclear [ 59].
