Sentence examples for be mediated by specific from inspiring English sources

Internal initiation of translation can be mediated by specific internal ribosome entry site (IRES) elements that are located in certain mammalian and viral mRNA molecules.

In developmental biology, it has been well established that multiple TFs generally work in a cascade-like manner and development proceeds in a stepwise manner.21, 35,36,37 Accordingly, we expected stepwise differentiation from hESCs to the primary ectoderm, to ocular surface ectoderm, and then to LGE, each of which can be mediated by specific TFs.

This could be mediated by specific lipids that participate in the regulation of neuroinflammation, including cannabinoids and omega lipids [16], [19].

The eMV-absorption by 2C T cells was found to be mediated by specific dual receptor/ligand interactions of 2C TCR with a cognate pMHC (Ld/QL9 or Ld/p2Ca) plus LFA-1 with ICAM-1.

A secondary question addressed by the study was whether the influence of the relative size manipulation on priming and explicit memory could be mediated by specific associations between the objects in each context-target pair or by relative size per se.

For other growth factor receptors, down-modulation of their surface expression has been shown to be mediated by specific amino acid motifs in the receptors themselves and/or involve the recruitment and association of adaptor proteins with the receptors which then target the receptors to intracellular compartments for degradation, recycling, or both [28].

Discrepancies in the genes activated in resistant and susceptible cultivars suggest resistance is mediated by specific molecular signalling pathways, known resistance (R) genes, and involves the production of hydrogen peroxide and initiation of programmed cell death around sites of infection.

Cellular uptake of folate is mediated by specific carriers or receptors, including FRα (folate receptor alpha; also known as Folr1 and Folbp1)3, proton-coupled folic acid transporter (PCFT), and reduced folic acid carrier (RFC) (see ref. 4 for review).

Alternative exons are often regulated according to cell-specific patterns and regulation is mediated by specific sets of cis-acting elements and trans-acting factors.

Oxygen sensing is mediated by specific prolyl-4-hydroxylases that regulate protein stability of the alpha subunit of oxygen-responsive transcription factors from the HIF family.

The interaction of cells with the implant is mediated by specific integrin receptors and includes their interrelationship with the microtopographical features of their substrate.