Rule 3: Gene deletion/movement may be mediated by single-/double-stranded illegitimate recombinations.
This study examines the influence of antigen binding affinity on potency in various immunotoxin fusion proteins where target antigen binding is mediated by single chain antibody variable region fragments (scFv).
To evaluate whether inhibition was mediated by single infected cells, we added serial threefold dilutions in replicate wells as depicted schematically in Figure 3A.
The infection cycle is biphasic; after the initial infection, viral spread to different tissues within an individual host is mediated by single virions, known as budded virus (BV).
A study established that cell cycle arrest in G2-M after thiopurine treatment was mediated by single-strand breaks in MMR-proficient cells [ 52].
How these diverse NIF responses can all be mediated by a single photopigment has remained a mystery.
The overall patterns of the trajectories indicate that light-driven chemotaxis can be mediated by a single OSN in the background of 21 functional OSNs.
That the larva uses the same strategy to respond to a variety of stimuli suggests navigation may be mediated by a single circuit that combines input from the various sensory organs.
During our analysis comparing proliferation rates of haploid progeny after loss of FZO1, the suppressive phenotype of four presumptive sfa alleles did not appear to be mediated by a single allele segregating in a Mendelian fashion.
To test whether nose touch response might be mediated by a single sensory neuron (ASH) and to check the role of the non-amphid neurons, we assayed nose touch response in FLP-ablated, OLQ-ablated, FLP/OLQ-ablated and FLP/OLQ/ASH-ablated animals in both C. elegans and Caenorhabditis sp. 3.
