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3MH release, on the other hand, appears to be mediated by more than one gene (Roncoroni et al. 2011; Thibon et al. 2008), therefore it is reasonable to speculate that the treatments in our study have differentially regulated release of these thiols.
Although these ABDs are highly homologous, their effects are therefore likely to be mediated by more than mere binding to actin.
In an FMDV infected cell, a possible 3AB 2C interaction could be mediated by more than one VPg copy, and the alteration in the number of VPg copies or their amino acid sequence could perturb these 2C 3AB interactions.
In the present study, we anticipated that the selective cancer cell-killing effect of i-Extract or Withanone is likely to be mediated by more than one genes/pathways and hence undertook an unbiased loss-of-function approach wherein gene knockdown was achieved by hammerhead ribozymes.
Specifically, we proposed that rule-selection be mediated by more rostral lateral prefrontal cortex and interconnected parietal cortex, whereas action-selection be mediated by more caudal prefrontal cortex, premotor regions and their parietal connections.
These results suggest that the pathogenesis of SSc in patients with anti-topo I might be mediated by more severe vascular damage compared with those with anti-RNAP.
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This finding is consistent with the hypothesis that the relationships between Family Background and adult outcomes are mediated by more proximal individual characteristics.
We also investigate the extent to which those relationships are mediated by more proximal variables such as Cognitive Skills and Educational Attainment.
Spontaneous development of intestinal inflammation in many different kinds of genetically engineered mice as well as the presence of numerous susceptibility genes in humans suggests that inflammatory bowel disease (IBD) is mediated by more complicated mechanisms than previously predicted.
Rather, it is mediated by more general motor circuitry (according to the Vargha-Khadem hypothesis) or reward-based learning and working memory abilities (according to Lieberman) that are also involved in other learning tasks.
The transcriptional patterns of these genes during reaeration are varied, suggesting that this process is mediated by more than one regulator.
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