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The effect of nephropathy on diabetic retinopathy (8, 9) could potentially be mediated by elevated dimethylarginines because all three analytes are renally cleared and ADMA and SDMA are elevated by reduced renal clearance (7, 10).
The promotion of the angiogenic phenotype in these lesions is supposed to be mediated by elevated levels of pro-inflammatory and pro-angiogenic secretions (cytokines, chemokines and growth factors) from the KS spindle cells [1].
Interestingly, increased invasion appears to be mediated by elevated expression of MMPs through upregulated SDF-1 [ 11].
As a consequence, ripening-delay by Ethrel may be mediated by elevated auxin formation in the berry tissue.
This increase would be mediated by elevated intracellular levels of the actual cytotoxic metabolite phosphoramide mustard [ 71].
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This suppression was mediated by elevated apoptotic microparticles derived from dying cells during acute HIV-1 infection.
In addition, this process was mediated by elevated ROS levels via activation of NADPH oxidase.
The negative control of the adjacent TCA cycle fluxes was mediated by elevated product levels.
In co-cultures C. saccharolyticus fortified the trade of biofilm formation by C. owensensis, which was mediated by elevated levels of c-di-GMP in C. owensensis.
These effects are mediated by elevated muscle cAMP levels and are the result of a direct effect of levodopa action on skeletal muscle since the effects are observed in isolated muscle in tissue bath [ 40].
Probably in db/db mice the improved glucose homeostasis is mediated by elevated plasma insulin concentrations 150 minutes after the glucose load, thus supporting the notion of vaspin inhibiting action on hK7-mediated degradation of insulin in the circulation.
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be repressed by elevated
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