Sentence examples for be mediated by altered from inspiring English sources

Inactivation and eventual elimination of duplicated genes can be mediated by altered epigenetic regulation, deletions, TE insertions, and/or point mutations causing premature stop codons.

Thus, since n-3 LCPUFA intervention reduces n-6-LCPUFA and their metabolites, such as PGE2 [ 6, 23, 44], changes in T levels may be mediated by altered CYP19A1 levels.

Ischemia reduces the isomerization from A-M.ADP.Pi to AM*.ADP.Pi, altering the kinetics of crossbridge activation through a mechanism that may be mediated by altered TnT and TnI phosphorylation.

Those changes may be mediated by altered expression of NMDAR subunits and sonic hedgehog.

These learning effects are thought to be mediated by altered synaptic plasticity.

HNSCC progression to adjacent tissue and nodes may be mediated by altered glycoproteins and glycolipids such as MUC1 mucin.

The effect of these proteins seems mainly to be mediated by altering the access of telomerase to its substrate, the telomere (van Steensel and De Lange, 1997; Smogorzewska et al, 2000).

Instead the effect may be mediated by altering the amount of drug target in the liver as postulated by studies showing that VKORC1 5′ SNPs are correlated with liver levels of mRNA (Rieder et al. 2005) and with activity in a reporter assay (Yuan et al. 2005); however, a third study failed to show this (Bodin et al. 2005).

We found that this effect was mediated by altering the uterine resting membrane potential and action potential.

Many of the beneficial effects of CR are mediated by altering the expression of several HSPs, notably Hsp70, and the activation of heat shock transcription factor 1 [ 13- 15].

In light of the important role of miRNAs for regulating gene expression, it is likely that at least some of these profound changes in gene expression in obese Zucker rats due to carnitine supplementation were mediated by altering miRNA expression in skeletal muscle.