Sentence examples for be mediated at a from inspiring English sources

Over the course of evolution this conflict has come to be mediated at a genetic level, Dr. Haig's explanation goes, because the mother and the father have different interests.

Moreover, despite the observed benefits, CMCs were rarely present in the kidneys or hearts of treated SNX animals, whereas high numbers were found in the liver and spleen, suggesting that at least some of their effects may be mediated at a distance, possibly through the elaboration of diffusible factor(s) that inhibit(s) the actions of TGF-ß.

However, RNAi sensitivity can also be mediated at a general level, such as in the case of an rde-1 mutant, in which RNAi sensitivity is totally lost [ 11, 12].

At least part of the inhibitory response in the quadriceps appears to be mediated at a spinal cord level, as experimental knee pain has been shown to inhibit quadriceps H-reflex amplitude [ 24], a measure of spinal reflex excitability that is strongly influenced by spinal α-motoneuronal excitability.

Interestingly, a large percentage of the plant phytochemicals shows a high degree of chemical similarity with metabolites of the human colon metabolic network pointing out that the therapeutic effect of these plants could be mediated at a metabolic level; however, we should not overlook the high similarity between FDA drugs and plant phytochemicals and especially anticancer drugs.

While the pathway by which C5a increases MCP-1 expression is not well understood, it is dependent on C5a receptor-mediated activation of AKT in RAW 264.7 macrophages [ 23] and is mediated at a pre-translational level in other cells of the innate immune system [ 29].

This incoming information is specifically stored through the strengthening and weakening of these connections, and Woods' main research interest is understanding how this plasticity is mediated at a genetic level.

The twin findings that (i) in terms of amplitude and tuning, all three sensorimotor pairings are recalibrated in a very similar manner and (ii) the illusion transfers to un-adapted sensorimotor pairings, strongly suggests that our effects are mediated at a relatively late-stage in the sensory and/or motor processing hierarchy.

These effects are mediated at a molecular level by the nuclear glucocorticoid receptor (GR) [ 4], but recent studies have indicated that GR signalling is rheostatically regulated through tissue-specific metabolism of GR ligands.

This increase in SUCLG2 protein levels was mediated at a translational or post-translational level, given that there was no detectable increase in Suclg2 transcript levels by quantitative real-time PCR (qRT-PCR; supplementary material Table S3).

APRIL processing is mediated at an arginine-rich motif by furin, a ubiquitously expressed pro-protein convertase that processes many inactive precursors including hormones, growth factors and receptors [ 31].