This is not to say that each mouse did not expend a substantial amount of energy on activity, but that the expenditure induced by movement was masked by changes in other thermogenic processes.
Although the results from the RT PCR analysis support the [S]sulfate incorporation data, the effects of the exposure to the EMF may have been masked by changes in gene expression resulting from enzymatic digestion and associated events.
In summary, because of the shape of the psychometric functions, negative changes in nectar reward properties along one dimension, e.g., concentration, might be masked by positive changes along the remaining dimensions, reward probability, and volume, even when these changes decrease overall profitability.
Under these culture conditions, the differences in gene expression in primary fibroblasts from different tissues may be masked by the changes in gene expression induced during myofibroblast differentiation.
Also, some of the significant gene expression differences may be masked by large changes in gene expression that occur between stages during normal Fundulus development [ 61].
In several cases plant mutant phenotypes were found to be masked by the compensatory change in expression domains of genes with redundant functions, e.g. PINs [67] or ACS members [68].
For instance, the PCET mechanism of TyrZ and TyrD of PSII depends on pH and the presence of calcium and chloride; the PCET kinetics of Tyr8 of BLUF domains depends on the species; fast PCET kinetics can be masked by slow protein conformational changes, as in RNR.
However, we cannot rule out changes that would be masked by the dilution effect of non-recombined cells, changes confined to specific cellular compartments, or changes that might be more apparent later in development.
We hypothesised that localized changes to metal transporter expression in a sub-population of neuronal or glial cells may be masked by the lack of global changes to metal transporter protein levels and hence, performed immunofluorescent staining on fixed coronal cerebellar sections from control and CLN6 animals with antibodies directed against several metal transporters.
