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This apoptotic effect could be markedly potentiated by the use of LNCaP cells overexpressing the PKCα or δ isozymes.
The toxicity of carbon tetrachloride and chloroform can be markedly potentiated by prior treatment with ethanol or phenobarbital.
The ability of IL-6 to stimulate aromatase activity was subsequently shown to be markedly potentiated by the IL-6 soluble receptor [ 13].
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We show that the relaxant effect of the catalytic subunit in smooth muscle is markedly potentiated by the addition of the regulatory subunits of SMPP-1M.
11β-HSD activity in homogenates of brain subregions is markedly potentiated by addition of exogenous dinucleotide co-substrate in vitro, whereas in kidney or liver, activity is only marginally altered [86,139,179,180], perhaps reflecting lower levels of endogenous NADP(H) in the brain [82].
These responses were markedly potentiated in denervated control (DC) mice, in which the aortic depressor nerve and sympathetic trunk were sectioned before measurement.
However, in the presence of H2O2, this effect was markedly potentiated, suggesting that the increase in TPβ levels facilitated greater Ca2+ mobilization (Fig. 7A and B).
Conversely, CAGA12-luc activity was markedly potentiated in SCP2 cells overexpressing p21 in response to TGFβ.
These oscillations were markedly potentiated in the presence of 5 mM Ca2+ (red trace, Figure 3C).
This effect is believed to be potentiated by the synergy of DNIC and collagen.
In addition, synapses potentiated during training could not be further potentiated by experimental manipulations that would have otherwise induced LTP; that is, inhibitory avoidance training occluded LTP.
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