The numbers of sclerostin-positive osteocytes at the proximal and middle fibulae were markedly decreased by loading.
The corresponding yields of SSB and DSB were markedly decreased by the addition of 0.2 M DMSO, with a similar efficiency for each radiation type (Figs. 1 and 2).
When the 7th dose of HQT was given at 0.5 h before VPA, the AUC0 t and Cmax of VPA were markedly decreased by 65%and82%2%, respectively.
However, the energy dissipation was markedly decreased by 33% in HCC3 with the lower transverse bar ratio (E A = 7706 kN mm) or by 24% in HCC4 with the greater fiber fraction and lower transverse bar ratio (E A = 8796 kN mm).
Actually, our in vitro kinase assay clearly showed that MST1 kinase activity on histone H2B was markedly decreased by BRAFV600E.
We did note abundant lateral proliferation of the frontoparietal bone in the pre-metamorphosis stages; however, this proliferation was markedly decreased by the onset of frontoparietal bone ossification.
In addition, the transcriptional expressions of three T3SS effector genes (exoT, exoY, exoS), which are located elsewhere on the chromosome, were markedly decreased by 7.5-, 4.8- and 8.3-fold, respectively, in the spermidine transporter mutant.
We next observed that tumor GRP94 over-expression and tumor growth in BALB/c nude mice, which were inoculated with human gastric cancer cells MKN45, are markedly decreased by honokiol treatment.
To elaborate the role of Lyn in MCP-1 production, Lyn siRNA transfection was performed to assess the effect of Lyn on P. aeruginosa invasion (transfection efficiency >95%) [17], and our data show that MCP-1 was markedly decreased by Lyn siRNA (Figure 6A).
