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Because clinical lipid data can be markedly altered by co-morbidity and/or medication use, we have also developed an alternate phenotype, a modeled lipid trait constructed by censoring the longitudinal lipid data for each individual at the first medical record date linked to a relevant co-morbidity (e.g., diabetes mellitus) or lipid modifying medication (e.g., atorvastatin).
Collectively, these data show that the biologic properties of IBs seeded by the same pathogenic ataxin-1 protein can be markedly altered by its fusion to different protein tags and that accelerated IB formation was not cyto-protective in this experimental system.
When depletion occurs early in pregnancy, fetal brain formation can be markedly altered.
Adverse effects of individual metals can be markedly altered by dietary levels of other essential and nonessential inorganic elements, essential organic nutrients and other nonessential dietary components.
Whilst epithelial cell Na/K-ATPase activity for example may be markedly altered by such factors the myofibroblasts may also be considered responsive elements.
A division of labor among SCN compartments may be of particular importance given findings that the spatiotemporal organization of the SCN network can be markedly altered by both acute and chronic changes in environmental conditions (present results, [ 21, 55]).
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Using these devices, investigators have reported that the microcirculation is markedly altered in sepsis, alterations are more severe in nonsurvivors, and persistent microvascular alterations are associated with development of multiple organ failure and death [14 17].
Using these devices, investigators have reported that the microcirculation is markedly altered in sepsis, alterations are more severe in nonsurvivors, and persistent microvascular alterations are associated with development of multiple organ failure and death [ 14- 17].
In forested and agricultural landscapes with transition zones, microclimate and matter cycling are markedly altered.
As a result, the evolution track, geometric and geomorphological characteristics of the JDS were markedly altered in the short term.
By conventional 2-dimensional histomorphometric analysis, we have shown that cancellous bone architecture is markedly altered in hypoparathyroidism.
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