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This property has been demonstrated to result in perturbations in the intracellular redox cofactor levels NAD(P)+ and NAD(P H, which can be manifested in changes in yields of certain redox-related metabolic products [ 15, 21, 38].
Previous studies conducted by our group found MTX delivery alone to be inconsistent, providing further evidence that the therapeutic effects of MTX may not be manifested in changes in the cytokine milieu [ 25].
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Changes in the morphology of the gold layer after the annealing are manifested in changes of the gold and fluorine concentrations as observed in XPS spectra.
Several aspects of this warming are manifested in changes in the regional energy and hydrological cycles, which affect and interact with the biosphere and with socio-economic activities.
Aside from the traditionally recognized symptoms of hypoglycaemia (e.g. neuroglycopenic, autonomic and malaise symptoms) 2, some adults with Type 1 diabetes report both negative and positive mood changes 3– 6 and, in children, hypoglycaemia may be manifested in behavioural changes 7, 8.
Because of this, this strain was specifically grown under microaerophilic conditions to see if the reduced oxygen would be manifested in a gradual change of the proteome from aerobic to anoxic conditions.
Knowledge of the specific traits under selection is crucial to understand how evolutionary changes may be manifested in terms of growth, survival and reproductive capabilities of recreational fish populations, and to develop management strategies that account for potential changes on population dynamics and viability (Ashley et al. 2003; Francis et al. 2007; Jørgensen et al. 2007).
According to IPCC (2001a, b), changes will be manifested in some extreme climate phenomena indicating that extreme events, including flood and drought, will be increasingly frequent and severe in Africa, particularly in the Horn of Africa where Ethiopia is the core.
They described this switch as being manifested in dynamic changes that would be influenced by a number of local measures, including imbalance of excitation mediated by glutamate receptors and inhibition mediated by GABA receptors (an inhibitory receptor type), abnormal gamma frequency (25 100 Hz) oscillations and hyperactive ventral tegmental area (VTA)—thalamic-hippocampal loop.
Necking is manifested in significant changes in a characteristic length scale, e.g., the distance between equally spaced marks in the reference state may increases by factor of 2 in amorphous polymers and up to a factor of 10 in some semicrystalline thermoplastics.
The day to night transition is also marked by a switch in energy metabolism from photosynthesis to aerobic respiration, and in carbon metabolism from CO2 fixation to catabolism of glycogen, both of which are manifested in the changes in gene expression.
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