Sentence examples for be major regulators of from inspiring English sources
Besides controlling and regulating neuronal functions, increasing evidence suggests that EGC could be major regulators of IEB functions, similar to astrocytes controlling blood brain barrier functions [ 10].
Although the HIF-1α system that regulates erythropoietin secretion had been proposed in earlier studies to respond to oxygen radicals, the oxygen-regulated enzymes prolyl hydroxylase and FIH-1 were subsequently discovered to be major regulators of the HIF-1α system and Nox4 is not currently thought to be involved.
Because Rho GTPases are known to be major regulators of actin polymerization, cytoskeleton assembly and integrin function, we examined the effect of RhoH-deficiency on actin polymerization in the IS.
MiRNAs are shown to be major regulators of such modifications.
One possibility relies on the phosphorylation of serine-arginine rich proteins (SRPs) known to be major regulators of alternative splicing in colon cancer cells [ 52].
In mammals, cardiac activation of PPARs has yielded substantial attention due to the fact that PPARs have been proven to be major regulators of cardiac metabolism [ 10- 13].
Vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF) are major regulators of angiogenesis.
For example, Ets family TFs (Elf1/2/4 and Erg), which are among the highest scoring TFs in our analysis, are major regulators of EC function and angiogenic growth55, 56.
Another well-characterized chromatin state is established by polycomb group (PcG) proteins, which are major regulators of developmentally controlled gene expression in animals and plants5,6.
