Sentence examples for be major modulators of from inspiring English sources

Evidence is accumulating for diacylglycerols to be major modulators of substrate level control of metabolism [ 26, 27].

IL-1 and IL-6 are pleiotropic cytokines, which are known to be major modulators of the acute-phase response and which may increase the synthesis of positive acute-phase proteins, while decreasing that of negative acute-phase proteins [ 20].

Although in some cases TR polymorphisms do contribute to transcript abundance variation, these results argue that at least in this case, TRs might not be major modulators of variation in phenotype.

However, this assumption may not be valid for the [ATP]/[ADP] and [NADH]/[NAD+] ratios during ischemia/recovery, which are major modulators of several key metabolic reactions in cytosol and mitochondria.

Thus, dynamic microtubules are major modulators of the mechanical properties that affect fundamental processes such as cell adhesion and motility.

Regulatory molecules are major modulators of acclimation and adaptation; among them, microRNAs (miRNAs) are versatile and substantial contributors to regulatory networks of development and adaptive plasticity.

The small GTPases of the Rho family, cdc42, RhoA and Rac1 and their effectors are major modulators of actin polymerization in dendritic spines (Tada ' Sheng, 2006).

Most interestingly, this response was abolished by DNAse or RNA digestion, which indicates that endogenous nucleic acids are major modulators of type I IFN production [ 67].

Mutant alleles of the CYP 1A1 gene are major modulators of lung cancer risk among smokers, mediate gender differences in lung cancer susceptibility, and associate with an elevated risk for breast, prostate, colorectal, and oral squamous cell cancer [ 35].

Biogerontology, the science that studies aging, uncovered some important molecular pathways that are major modulators of the aging process (Kenyon, 2010; Fontana et al., 2010; Bartke et al., 2013).

N-methyl-d-aspartate (NMDA) and gamma-aminobutyric acid (GABA) receptors are fundamental for learning because they are the major modulators of the long-term potentiation, the electrophysiologic mechanism for learning.