The existence of differences between individuals in coding genes as well as in the control region, which are maintained between duplicates, indicates that recombination apparently occurs frequently, i.e., in every generation.
It draws on the principle that linkage disequilibrium (LD) tends to be maintained over many generations between loci which are physically linked to one another.
If exposure to 100 mM EMS were to increase the rate of compensatory mutation relative to lesser EMS concentrations, then selfing would likely permit the epistatic interactions between loci to be maintained for many generations [22], [23], [26], [32], [33].
In considering the mechanisms by which an induced increase in acetylation could be maintained across cell generations, it is important to remember that the measured level of acetylation represents a dynamic equilibrium between the activities of modifying and demodifying enzymes.
The initial selection response in line HFP could not be maintained in subsequent generations.
Genome integrity should be maintained from generation to generation to ensure proper cell function and survival [ 1– 3].
For the purpose of this review, ethnicity is defined as 'shared origins or social background; shared culture and traditions that are distinctive, maintained between generations, and lead to a sense of identity and group; and a common language or religious tradition' (pp 327, Senior and Bhopal, 1994).
