Focus is made on studies which have addressed the problems of how to manage the randomness and the variability of values of critical and follow-up headways, and how to depict the distribution of these gap acceptance parameters.
In order to increase the efficiency and accuracy of design optimization, many efforts have been made on studying the metamodel techniques for effectively representing expensive and complex models.
After characterizing the actual chemical composition of the hydrogels by XPS, efforts were made on studying the effect of the nature and content of amine functional group on the hydrophilicity and the surface charge of the gels.
It is known (see Sect. 20) that (B) can fail if (alpha < 1) (although this was not known in the 1970s), so in the 15 years after 1957, a lot of effort was made on studying problems (A) and (B) when (alpha >1).
In addition to these theoretical advancements, progress has been made on studying the hallmark of binocular rivalry - the temporal dynamics of rivalry perception.
Following review, decisions are made on study progression in accordance with the study's options, i.e. its design, adaptive features and boundaries.
Instead, a separate analysis was made on study subjects who participated for less than 50%% of the weeks, to see if their profile was different from that of the others.
For the QTc evaluation, ECG recordings were made on study drug administration days (as ECG profiles) at 60, 50 and 40 minutes pre-dose (to derive the period-specific baseline), and at 0.5, 1, 1.5, 2, 2.5, 3, 4, 6, 8, 12 and 24 hours post-dose (last three time points omitted for moxifloxacin treatment).
In the past few years, with the rapid progress in high throughput technologies such as microarray and massive parallel sequencing, many exciting new discoveries have been made on studying the genome-wide binding landscapes of different histone modification marks using ChIP-chip and ChIP-seq methods [ 1, 6- 11].
In providing national, regional, and global estimates, decisions need to be made on which study or studies are used for a particular country.
