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The uniqueness of those haplotypes relies on a very low number of mutations, clearly demonstrating the difference that can be made by sequencing the whole mitogenome compared to a subset of the mitogenome only.
While greater discovery of rare transcripts can be made by sequencing normalized mRNA pools, sequencing non-normalized samples enables one to obtain valuable information about changes in gene expression [ 13].
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Synthetic long reads are made by sequencing bar-coded ∼10 kb genomic fragments with standard Illumina short-reads, performing a local assembly of these 10-kb fragments into synthetic long reads, and then feeding them into a standard assembler (Voskoboynik et al. 2013; McCoy et al. 2014).
†Diagnosis was made by sequencing and analysis of the viral protein 1 coding region after RT-PCR.
Diagnoses were made by sequencing products obtained by PCR with primers for the 17-kDa protein (4 ), citrate synthase (4 ), and PS 120 protein (5 ) genes.
Rosid I and rosid II comparisons have been made by sequence homology between soybean marker sequences and Arabidopsis sequences [ 17].
For assessment, we remove close homologues to the sequence for which a prediction is to be made (by a sequence identity above a threshold).
Because it can be made by nucleotide sequences much longer than ∼10 bp, this idea is not contradictory to the absence of any core elements in the Coreless type.
In an exchange which copied in Sony co-chair Amy Pascal, Glickman requests that cuts be made by scaling back action sequences.
Nevertheless, recent works have shown that concordance improvements can be made by filtering for gene nucleotide sequence identity [ 1- 4], by suppressing lower intensity genes [ 5] or by aligning gene lists with continuous measures of differential gene expression [ 6].
A reasonable estimate of the compressibility of variable length DNA sequences can be made by considering all loss-less coding schemes of up to four bases.
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