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Combining X7Ab with TMZ allows the TMZ dosage to be lowered, without compromising therapeutic efficacy.
Recent preclinical and clinical studies have indicated that the CO2 content might be lowered without compromising increased tumour oxygenation and radiosensitisation.
If the patellar tendon insertion is too close to the proposed osteotomy, a proximally directed biplane osteotomy that will allow the level of the tibial osteotomy to be lowered without compromising the extensor mechanism can be made posterior to the tubercle in the tibial tubercle.
Furthermore, a lower FPG threshold is preferred if the cost of the intervention can be lowered without compromising too much effectiveness.
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The relevance of our findings is that lowering body temperature may be done safely without compromising the immune response in patient groups who are thought to benefit from regulating body temperature.
(24) For our current system, we also lowered the concentration of glucose oxidase to see if a similar pH stability can be achieved without compromising the dye photostability (see the section below on photobleaching time analysis).
This makes the climate change problem unique in the degree to which compliance flexibility can be used to lower costs without compromising environmental integrity.
We believe that, with proper planning, that amount could be doubled without compromising other financing streams.
"Competition needs to be introduced without compromising safety," says Terje Thorjussen, president of the West Gulf Maritime Association.
This can be done without compromising production efficiency.
Therefore the energy consumption must be minimized without compromising the quality of service.
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