Given that the olfactory bulb is continuously replenished with newly generated neurons [33], [34], our observations imply that GFP fluorescence is lost with aging of neurons.
69 This result is potentially beneficial for older adults, even in the frail elderly patients, whose muscle mass is lost with aging and accelerated with impaired fasting glucose and diabetes.
Another study on mice 23 showed that IGF-1 can stimulate the expression of RANKL and M-CSF in young but not old animals; therefore, the regulatory role of this growth factor is lost with aging.
Because there are strong biologic rationales for evaluating the directionality of the relations between BMD and tibia lead in both directions (e.g., lead in bone is toxic to bone cells, thus influencing BMD, whereas bone mineral is lost with aging, thus influencing the denominator in the bone lead concentration measured by XRF), we created models to do so.
However, this capability seems to be lost with age, and the likelihood of defective wound healing increases significantly.
While there is speculation in the literature that the protective effects of estrogen on the regulation of arterial pressure in females may be lost with age, this assumption is based upon the evidence obtained from adult OVX animals.
Young stems are covered in hairs, both short and soft, and long and coarse; these are lost with age.
In newborns, the sting is preceded by a small dorsal fin; the fin is lost with age, though it may be evidenced by a small ridge or scar.
The protective role of the AT2R depressor pathway is lost with age in female mice.
First, DAPI staining of three nuclei in the tail is lost with age (Fig. 1a,b).
