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The significance of these studies is that concentrations of plasma uric acid can be related to measures of oxidative stress, which can be linked to tissue aging.
The reemergence of these genes appears to be linked to tissue repair, but when an imprecise interaction of developmental and inflammatory signals occurs, complete healing is not achieved.
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NTS expression is also found in endocrine tumors and is linked to tissue differentiation [9].
Integrins are linked to tissue invasion by hepatocarcinoma cells [9] and play a role in apoptosis [10].
For an example, in case of tuberculous meningitis, increased MMP-9 expression is linked to tissue destruction, a pathological hallmark of inflammatory host immune response [4] [5].
Any alteration in this balance is linked to tissue damage.
Angiogenic growth factors have recently been linked to tissue metabolism.
Further, it is known that Hmox-1 expression is linked to tissue stretch.
Normal physiology suggests that cardiac output is linked to tissue metabolic requirement.
Recently, MRS lipids were linked to tissue hypoxia in tumours (Zoula et al, 2003).
In parallel, we have also identified a number of up-regulated genes that are linked to tissue protective and immune counter-regulation mechanisms.
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CEO of Professional Science Editing for Scientists @ prosciediting.com