Shear thinning of well-dispersed suspensions can be linked to the modifications in the structure and arrangement of interacting particles [37].
As stated, MGO has not only been linked to the modification of proteins, but has also been shown to directly modify and damage DNA.
Nevertheless, our analysis successfully identifies nearly 1,500 TOMM gene clusters, with the vast majority of the cognate precursor peptides being linked to the modification machinery.
PC2 stresses differences between oligodendrogliomas (O) and other gliomas and is linked to the modifications of the genomic status of genes located on 1p and 19q.
We then considered the somewhat less likely hypothesis that the signal leading to asymmetric methylation could be linked to the covalent modification of histones established during spermatogenesis.
This oxidative modification can be linked to the activity of Grx1 [ 187], since the depletion of Grx1 results in an increased S-glutathionylation rate along with the induction of apoptosis, while Grx1 overexpression causes opposite effects.
In contrast, F/R provoked a robust band-shift that was ablated by co-treatment with H-89 (Fig. 3B), indicating that PKA activation is linked to the post-translational modification of ezrin, possibly through phosphorylation.
This is reasonable because the products are linked to the substrate by electrochemical modification.
Fraga et al (2005a) found that loss of monoacetylated lysine 16 and trimethylated lysine 20 forms of histone H4 is a global hallmark of human cancers, and in prostate cancer, global patterns of histone modification are linked to the risk of prostate cancer recurrence (Seligson et al, 2005).
Thereby, the solid support material is attached to the 2′-hydroxyl group of the adenosine moiety (representing A76 of the tRNA 3′-terminus); the corresponding amino acid (representing the C-terminus of the peptide chain) is linked to the ribose 3′-amino-3′-deoxy modification via an amide bond.
