In all, 2457 disease phenotypes could be linked to surface-exposed peptide residues in CREDO, 1130 of these could also be directly linked to peptides interacting across protein protein interfaces, 1012 to protein ligand-binding sites and 44 to protein ligand-bindingroovesites
We relate this incision history to a tectonic setting where an increase of drainage area of the Mur river due to stream piracy in Late Miocene to Pliocene times is linked to surface uplift.
Thermokarst lake formation is a dominant mode of permafrost degradation and is linked to surface disturbance, subsequent melting of ground ice, surface subsidence, water impoundment, and positive feedbacks between lake growth and permafrost thaw, whereas lake drainage generally results in local permafrost aggradation.
Diving depth in the Gulf Stream may have been linked to surface water temperatures, but the causal relationship was unclear.
In several previous studies, T cell function was linked to surface expression of markers such as CD27 and CD62L, among others [24], [26] [29].
The observed wettability variations appear to be linked to the surface coverage of the powder by the deposit.
And so, people made a lot of exploratory development by using carbon nanoparticles to seek new photographic materials [14 16], but there also a problem that some special ions or groups must be linked to the surface of nanoparticles to achieve image effect in vivo.
At the first method, the biomolecules consist of a thiol group that can be linked to QD surface by mercapto-exchanging process but the cross-linker between Zn and thiol is not tight and dangled, therefore they easily dissociate of QD surface and result to the aggregation of it.
Groups of contiguous co-evolving residues form networks or 'sectors' which are spatially organized within the protein and they can be linked to many surface sites distributed throughout the structure.
Next, we analysed whether the observed preferences for either TRAIL-R1 (HeLa, Colo357) or TRAIL-R2 (Colo205, BxPC-3, AsPC-1) could be linked to the surface expression levels of the two receptors.
