Sentence examples for be linked to pathogenic from inspiring English sources
In this study, we describe new features of human macrophage cell death induced by A. actinomycetemcomitans leukotoxin that that can be linked to pathogenic mechanisms of inflammatory-related diseases.
In summary, our results suggest that the genetic markers identified with multivariate phenotype highLDLhighTG have phenotypic associations with common traits in MS. The common traits in MS, particularly hyperlipidemia, may be linked to pathogenic associations with osteosclerosis and neurodegenerative disorders including AD and PD influenced by pleiotropic genetic factors.
Second, the pathogenic effects of CTRC variants are linked to pathogenic CFTR and SPINK variants resulting in multiple defects in regulating intra-pancreatic trypsin.
This ability to detect and respond to dead cells has recently been linked to pathogenic responses induced after ischaemic stroke and traumatic brain injury [ 61,62].
The miRNAs formed groups with 1st-to-3rd tier associations with genes involved in biological processes and pathways regulating tissue organogenesis and immune response, processes that have been linked to pathogenic mechanisms of biliary atresia [ 2, 5].
In several instances, this also led to the identification of genes or classes of genes that could be linked to the different pathogenic properties of the two strains of SDE and the taxon SDD.
Together these findings provide in vivo evidence that the D620N mutation likely confers pathogenicity through a partial loss of function mechanism and that this may be linked to other known pathogenic mechanisms such as mitochondrial dysfunction.
Thus, it was important to examine a cohort of patients with early synovitis to determine whether AGE-damaged proteins were present near disease onset, in order to determine whether the generation of AGEs could be linked to an ongoing pathogenic process or whether they are merely the consequence of damage in the past.
SIV-associated comorbidities occur in the absence of conventional risk factors for CV disease and in the absence of ART and can be linked to persistent inflammation characteristic to pathogenic HIV/SIV infection.
These differences could be linked to the loss of pathogenic islands in some of the isolates, as has been recently reported (22 ).
