Sentence examples for be linked to metastasis from inspiring English sources
A similar study by Li et al., showed promoter methylation of p16 (47%), RASSF1A (41%) and DAPK (21%) in a cohort of 60 patients with ACC and indicated that RASSF1A may be linked to metastasis potential in ACC [7], [8].
Although the loss of BAP1 function may be linked to metastasis, the precise mechanism of tumour dissemination in UM is still unclear.
To determine if loss of PKD1 can be linked to metastasis, first we analyzed the methylation status of the PRKD1 promoter in primary tumors from patients with IDC who were diagnosed with positive or negative dissemination to lymph nodes.
95 Of particular relevance, the c-Met pathway activates a program of cell dissociation, cell motility, and protease production, which can permit tumor cell invasion and cell scattering that may be linked to metastasis.
The XIAP expression has been previously shown to be linked to metastasis and tumour aggressiveness in other solid tumours (Kluger et al, 2007; Shi et al, 2008; Gu et al, 2010).
Increased MYO10 and Src protein expression and/or activity have been reported independently in breast cancer and are linked to metastasis and poor patient survival13,15,31.
While many gene changes have been tied to the early stages of cancer development, this is one of only a few that have been linked to metastasis, notes Jeffrey Trent of the National Human Genome Research Institute in Bethesda, Maryland.
A number of these genes mapped to chromosome 7, whose gain has been linked to metastasis and poor prognosis in patients with non-small cell lung cancer and peripheral nerve sheath tumors [23], [24].
