Sentence examples for be linked to epigenetic from inspiring English sources
It has been suggested that male infertility might be linked to epigenetic alterations.
However, functions of GAGA-motif binding proteins are more diverse and can also be linked to epigenetic regulation of homeotic genes e.g. by recruiting silencing factors to specific sites, as well as influencing the promoter-proximal pausing of RNA Polymerase II (Pol II) [5], [9], [10], [11].
As direct and reciprocal hybrids are bona fide identical at the nuclear level, different levels of F1 fertility depending on cross directionality could be linked to epigenetic factors.
This finding concurs with the documented reduced expression of antisense transcripts from the X chromosome and suggests that in a biologically relevant cellular context convergent transcription may be linked to epigenetic gene silencing.
Based on previous data reporting an epigenetic regulation of BECN- 1 in BC and our data showing a deregulation of DNA methylation in our BC samples (Fig. 2a, and Additional file 1: Figure S1), we hypothesized that the loss of GABARAPL1 expression in BC might be linked to epigenetic modifications.
What you eat, what your mother ate, the age when your grandfather started smoking, the amount of pollution in your neighbourhood – these factors have all been linked to epigenetic changes that get passed down through the generations.
The increasing numbers of investigations revealed that the expression level of SM gene clusters has been linked to epigenetic mechanisms, which are functionally relevant changes to the genome that do not involve in a change in the nucleotide sequence (Fuchs and Quasem 2014).
miR-200c and miR-141 expression is lost in different types of cancer cells [5], [11], [20], [21], and we sought to determine if this loss of expression was linked to epigenetic changes in the miR-200c/miR-141 miR-200c/miR-141 miR-200c/miR-141 CpG
We observed transcriptional changes similar to the gene expression signature of synovial sarcoma, principally involving genes whose regulation is linked to epigenetic factors, including imprinted genes, genes with transcription start sites within a CpG island and chromatin related genes.
In these cells, SYT-SSX primarily affects the expression of genes whose regulation is linked to epigenetic factors, including imprinted genes, genes with transcription start site (TSS) within a CpG island, and chromatin related genes.
