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Furthermore, such knowledge should allow us to focus on haplotypes with allelic differences in expression that may be linked to complex traits and common diseases.
Genome-wide linkage scanning is a comprehensive and unbiased approach to identifying chromosomal loci that may be linked to complex diseases [ 5].
The greater benefit in smokers and in those who had not yet had a cardiovascular event appears to be linked to complex motivations for including medication as part of a wider strategy for healthy living.
This approach is consistent with recent recommendations of the authors of The Lancet's Stillbirths series, who advocate a consensus "on a limited number of programmatically relevant, comparable causal categories,… that can be linked to complex classification systems and ICD codes" [ 23].
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Such disorders are linked to complex factors.
This photoactivity is linked to complex surface groups containing nitrogen, sulfur and oxygen in various configurations.
Although many have recently been linked to complex human traits, the underlying mechanisms for most of these transcripts remain undetermined.
Organic bases in crude oil have been linked to complex interfacial phenomena that could affect the multiphase flow of these fluids in subsurface systems.
Infiltration through sediments is linked to complex biogeochemical processes occurring at small spatial scales, often leading to a progressive reduction in infiltration rates due to microbial growth and/or mechanical clogging.
Once genes or genetic variations have been linked to complex diseases, the next challenge is to find out "what they are doing in normal conditions, what it means for the gene, and in general for human beings," says Benítez.
Some researchers (Haldoupis et al., 2004, 2006; Mika et al., 2005; Kumar et al., 2008; Mika and Haldoupis, 2008) studied nighttime early/slow events and showed that the gradual onset of such perturbations is linked to complex and dynamic lightning activity, composed of a few CG return strokes and clusters of IC discharges, which produce primary and secondary ionizations, respectively.
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