These observations would suggest that some of the epigenetic changes induced by alcohol may be linked to alterations in the activities of genes responding to ROS [ 15, 20].
We also addressed the possibility that the ability of CBS to delay cellular senescence may be linked to alterations in the level of homocysteine (Hcy).
Under these terms, the sample studied is not indicative of the whole spectrum of handedness, but conversely the participants belonged to well-defined subpopulations and, thus, any group differences could be linked to alterations in brain organization related to handedness.
Our work aims to investigate whether a similar phenomenon may be occurring in the bovine model, and whether this may be linked to alterations in cell signaling and subsequent physiological processes.
Therefore, the MbMt-hypermethylated subregions of TBX1 at the beginning and end of the TBX1c isoform indicated in Figure 3 might be linked to alterations in the gene's higher-order structure via CTCF.
Mitochondrial dysfunction has been demonstrated in the neurons of AD patients [ 7] and further shown to be linked to alterations in ROS production [ 8]; many of these biochemical defects in the brain appear to be reflected in peripheral blood cells [ 9].
Ground based timber harvesting on wet sites has been linked to alteration of soil properties that may result in reduced long term site productivity.
The decrease in NEP expression has been linked to alteration in Aβ clearance leading to Aβ accumulation, which is considered to be an important event contributing to the development and progression of AD [7].
The activity exerted by PgD5 against the phytopathogenic fungi and S. cerevisiae was linked to alteration of fungal membrane permeability.
Then, we determined whether down-regulation of CerS1 transcription is linked to alteration of endogenous Sp1 recruitment to the promoter in UM-SCC-1 cells compared to keratinocytes using quantitative-chromatin immuno-precipitation (Q-ChIP).
