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For some QTL, both Coda and Brundage contributed favorable alleles, but for different end-use quality traits, indicating these alleles may be linked in repulsion.
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This could be due to a pleiotropic effect, closely linked genes or the genes for biomass and quercetin accumulation being linked in repulsion phase.
A total of 30 LGs were linked in repulsion with other LGs.
If the segregation distortion locus and the QTL for the agronomic trait are linked in repulsion, the agronomic QTL will be underrepresented or in the most extreme case absent from the population.
Note however, that our experiment lacks the resolution to exclude the possibility of pseudo-overdominance, which occurs when two partially dominant loci are linked in repulsion phase, inflating estimates of dominance effects.
With the exception of yield, we found that each of these traits was controlled by two or three QTL within the region of chromosome 11 introgressed from S. habrochaites, with the QTL alleles being linked in repulsion phase in relation to disease resistance QTL alleles.
The pseudo-overdominance model operates when two or more dominant or recessive mutations in different parents are linked or "in repulsion".
Introduction of a 2-position heteroatom in pyridine analogue 22 resulted in a fivefold decrease in enzyme potency, which could be linked to repulsion between the pyridine nitrogen and the pyrazole ring's 5-nitrogen atom, resulting in an altered conformation about the pyrazole-pyridine bond.
Recombination suppression inhibits accurate QTL mapping, positional gene cloning, MAS, and identification of recombinant genotypes with favorable combinations of alleles that are originally linked in repulsion.
This may be linked to reversible conformational changes in the apoenzyme at alkaline pH arising from electrostatic repulsions in the active site, which break a buried Arg-30 Asp-299 sArg-30 Asp-299 bring Arg-30 to the saltace.
Among sites 2834, 2838, 2845, and 2858, a complex, nontransitive pattern is observed in which site 2845 appears to be linked to 2834 at time points 1 and 3 even though site 2838, which is linked to 2845 in most samples, appears to be in repulsion with site 2834 across all samples.
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