Sentence examples for be likely to bind from inspiring English sources
By definition, an uncompetitive inhibitor binds to the enzyme-substrate complex and hence would be likely to bind close to the active site of the enzyme.
Ninety-five of 3,433 WN virus peptides scored above a predetermined cutoff, suggesting that these would be likely to bind to HLA B*07 and would also be likely candidate CTL epitopes.
From the N&B, we obtained concentrations of eGFP-CaM in the μM regime; only very high affinity targets (kD ∼ nM or below) would be likely to bind and stay as a complex during the time frame of the fluctuations (∼4 s between frames).
The link between determining binding specificity and finding sites where the transcription factor is likely to bind is the way in which binding specificity is represented.
All of these compounds are likely to bind in an inter-subunit binding cavity at the top of the TMD which imposes an upper size limit upon them (Stevens et al., 2005; Nury et al., 2011).
A binding pocket that is likely to bind a ligand will have an Sscore greater than 0.8 and a Dscore greater than 0.83 [44] 44].
These inhibitors do not block the N-terminal domain's ATP-binding site, and thus are likely to bind at the C-terminal domain.
Hence, these nine different descriptors are suitable for formulating a scoring function that can differentiate between small molecules that are likely to bind kinases (actives that have kinase-likeness) and those that are not.
One way to solve this question is the use of enantiomeric substances, as enantiomers have the exact same physical properties, but are likely to bind with different affinities to proteinaceous and thus chiral binding sites.
CTCF is a sequence-specific Zinc-Finger DNA binding protein [28], and we thought it was likely to bind the rDNA directly.
The object was to find fragments with affinity to the ATP-binding site, which would produce a set of fragments that were likely to bind to GAK or other kinases due to the conserved nature of the ATP-binding site.
