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Since dif XerC is more variable than dif XerD, we then wondered whether XerC recombinases would be less well conserved than the XerD proteins.
Behavioral phenotypic traits seem to be less well conserved than physiological traits, which may explain why not all grasshopper species within the subfamilies of Cyrtacanthacridinae or Oedipodinae display phase polyphenism [27] [29].
The extracellular domains of WAK/WAKL proteins have been reported to be less well conserved than their cytoplasmic domains [21] [23] and it was proposed that these variations in combination with their specific expression patterns may provide Arabidopsis with the ability to detect and respond to a diverse array of ligands [18].
Finally, functional cryptic splicing motifs occurring deep within the introns can be challenging to identify, because they tend to be less well conserved than natural splice sites.
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Alignment of 98 S-rich prolamin amino acid sequences illustrated that four cysteines were preserved nearly 100% and four cysteines were less well conserved.
This is particularly true of lytic genes; latency-associated genes are less well conserved.
The NLS is less well conserved in all UNC-76 sequences.
The Thr16-Ser17-Arg18 region of CCL3 is less well conserved between species.
Interestingly, however, the residues around the EPG modification site, Glu362 in T. brucei [27], are less well conserved (Fig. 1).
With respect to sequence homology, E1a and E1b were less well conserved among species than were the other GATA4 coding exons, especially E2 (Figure S1).
Lack of conservation may limit the application of our approach to most genes, which are less well conserved than heat-shock genes [55], [56].
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