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In our patient group the highest PCI with complete cytoreduction was 18 and the lowest in the group with incomplete cytoreduction was 22, indicating that complete cytoreduction seems to be less probable in patients with extensive PC depicted by MRI.
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Hence their action is less specific than conventional antibiotics, which means that development of drug resistance by pathogens is less probable in such case.
Another hypothesis is that tumour compression of the infundibulum and superior pituitary arteries may cause infarction of the normal pituitary gland; however, ischaemia of the tumour mass itself is less probable in this case because the vessels supplying the adenoma are attributable to the inferior pituitary circulation [38].
Neurological adaptations due to chronic pain are less probable in adolescents, and acute pain (point prevalence) was not asked for.
The scenario that both sub-families diverged in Tibet as they colonized the upper Yangtze and Mekong rivers, respectively, is less probable in the light of the current data.
However, this bias is less probable in our study, since we included guidelines from several countries, differing in funding and reimbursement [ 97, 98], availability and accessibility [ 99, 100] of healthcare.
We have considered these further scenarios to be less probable, because they may result in a less robust control due to an unlikely fine-tuning of two parameters.
Since an impact of this silent 425T>C polymorphism on CDA enzyme activity was expected to be less probable, we did not include this polymorphism in our investigations.
Similarly, production of naphthalene from benzene via HACA was also found to be less probable.
A known proposition cannot be less probable than an unknown proposition.
Then any truth that goes beyond the evidence will be less probable than the evidence.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com