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Despite having been isolated from human beings [ 2], this biovar 2 seems to be less pathogenic for humans than the biovars 1 and 3 [ 3].
Thus, these lineages may be less pathogenic for humans.
In addition to the African outbreaks, the species Reston Ebola virus, which may be less pathogenic for humans, was isolated from cynomolgus monkeys imported from the Philippines to the United States (4).
Regarding the distribution of strains within cluster 4 (4 cat strains from the United States, 10 cat strains from France, and 3 cat strains from Germany, but no human strain), we speculate that these strains may be less pathogenic for humans or that a sampling bias occurred.
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Similarly, R. africae is less pathogenic for humans than other SFG species such as R. conorii and R. rickettsii, in particular because the infection is never lethal [ 17].
Thus, among the C. canimorsus and C. canis strains, the proportion of strains able to cleave IgM N-glycans was very different, reinforcing the hypothesis that C. canis are less pathogenic for humans than C. canimorsus.
Some studies have revealed that the roles of subcutaneous abdominal fat in CVD risk factors or atherosclerosis are nearly identical to those for visceral abdominal fat, whereas other studies showed that subcutaneous abdominal fat may be "less pathogenic" or protective for CVD [ 6- 9].
Chrysotile asbestos is less biopersistent and is considered by many to be less pathogenic than amphibole asbestos.
This lack of inflammatory cells appears to be less pathogenic to the liver cells [ 1- 5].
HIV-2 is less pathogenic in nature and therefore is likely to be safer for vector design and production.
It has been shown [ 4], that genotypes of phylogroup 1 are pathogenic for mice when injected by intracranial and intramuscular routes, while Lyssaviruses from phylogroup 2 are less pathogenic by the intramuscular route.
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CEO of Professional Science Editing for Scientists @ prosciediting.com