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Under the dedifferentiation hypothesis of cancer development, cancer cells are postulated to be less differentiated than their progenitor cells but often resemble their tissue of origin phenotypically [ 5].
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When differentiation was induce before the cells had reached confluence, cells were less differentiated than under "classical conditions" and C/EBP-α was expressed at low level, that did not allowed quantification.
(2) The structure of comparative self-rating in adulthood is less differentiated than the structure of perceived comparative parental evaluation.
A disadvantage is that the criteria are less differentiated than in a conventional environmental impact or suitability assessment.
The researchers would want to find that the facial muscles of Africans were less differentiated than those of Europeans.
In general, geographically adjacent clusters were less differentiated than geographically more distant groups.
Morphology analysis showed that HGT-1 tumours were less differentiated than L50 cells, which also appeared more rounded.
These tumours were less differentiated than the patient's original tumour, suggesting the occurrence of EMT (data not shown).
Nm23-H1-negative tumours and tumours with moderate focal staining intensity were less differentiated than tumours with strong homogeneous or moderate homogeneous staining intensity (P < 0.05).
The tubular subtype is the most differentiated form and the second most frequent, and the cribriform subtype is less differentiated than the tubular subtype and the most common pattern.
Consistent with the expected effect of purifying selection, sites in long introns and 0-fold sites in conserved genes are less differentiated than those in short introns and less conserved genes, respectively.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com