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Education is the most frequently used proxy, but this may be less appropriate in a three-generation study.
Therefore, deterministic complete linkage disequilibrium modelling would be less appropriate in this case.
For example, these materials might be very useful for modifying orthopedic hardware when the bacterial load is not overwhelming but might be less appropriate in a polymicrobial, high bacterial load environment such as the oral cavity or gastrointestinal tract.
Since the migration pattern of the femoral head in acetabular dysplasia and DDH is usually in the superior direction, the K&L grading appears to be less appropriate in such patients.
This strategy of maximal viral suppression may be less appropriate in a context in which the second-line treatment may be considered as the last chance for a suppressive regimen.
It is developmentally appropriate for carers of young people to provide meal support whereas this may be less appropriate in the case of adults with a severe enduring illness.
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Moreover, it is not even clear that the questionnaire would be less appropriate if one were to define empathy in a purely affective manner.
This method is less appropriate in hunted game from which trophies are systematically collected.
GPs felt that adherence to guideline-recommended preventative measures was less appropriate in the case of older patients with multimorbidity and patients with a limited life expectancy.
Treatment duration was less appropriate in female patients: in general their treatment durations were shorter than recommended in the national (10 days) and local hospital guidelines (varying between 7 -14 days).
Even though the value of early intervention in RA has been appreciated for a long time, the diagnostic criteria applied for a diagnosis of RA are less appropriate in early disease [ 4, 5].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com