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(The final cranial window has a clear aperture of ∼3-mm diameter.) During imaging, the mouse head was carefully aligned to make the cranial window and the brain maximally perpendicular to the microscope objective optical axis, so that the spherical aberration caused by the cranial window can be largely compensated by the correction ring on the objective (Supplementary Fig. 4).
Given noisy spatiotemporal samples, the MAE, and thus percentage errors, for all algorithms increases but this increase can be largely compensated by increasing K; as an example, the average percentage error at 20 dB for the activation time estimate using the quantized distributed estimation drops from around 48%% (at K=1) to around 28%% (at K=3).
This suggests that the relative instability of the *300A variant protein can be largely compensated for by endogenous levels of ATG16L1*300T, or perhaps suggesting that ATG16L1*300A is only targeted within a functional ATG5/ATG12/ATG16L1 complex while over-expressed ATG16L1 only inefficiently incorporates into pre-existing ATG5/ATG12/ATG16L1 complexes as suggested by Fujita et al [14].
This shows that the absence of an assembled genome can be largely compensated for provided sufficient read coverage.
High illness burden is a necessary cause of high inpatient utilization; but it is not sufficient, and can be largely compensated for with good inpatient utilization management.
Fertility decline during economic recessions are seen as a result of childbearing postponement, especially of first births, which can later be largely compensated during times of economic prosperity (Neels 2010).
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We argue that upon the structural change of a protein, the gain or loss of the intramolecular energy is largely compensated by the loss or gain of the hydration energy, when the folding is considered under the isochoric condition.
For example, the disappearance of the American chestnut (Castanea dentata) in many forests in eastern North America due to chestnut blight has been largely compensated for by the expansion of oak (Quercus) and hickory (Carya) species, although there are certainly commercial consequences of this replacement.
The slightly increased complexity at market level (i.e. each market launching up to two of the three products of the portfolio) is largely compensated by the simplification at a global level and the insurance to please many more consumers with products that are liked for their differentiating sensory properties.
Weed competition caused a severe reduction of DM yield and lucerne proportion in the 'organic' management but just a slight, non-significant reduction of seed yield, for which the greater stand thinning in this management relative to the chemically weeded one was largely compensated by increases in racemes per stem and seed weight.
Both effects show a similar spatial pattern but with opposite sign, indicating that—on a global scale topography and bathymetry are largely compensated by the Moho mass anomalies.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com