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These genes appear to be key in regulating radiation response and therefore these pathways or their upstream regulators may prove to be a good predictor of treatment outcome.
These results further suggest that an increase in influenza MOI in rDC following high vs. low dose infections may be key in regulating the magnitude of the adaptive CD8 T cell response [7], [8], [9], [11].
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While this study did not examine how IGF1-IGF1R levels influenced cellular behavior, this more complex model also suggested IGFBP levels were key in regulating receptor-ligand complex levels.
The large number of plant Puf protein family members suggests that these proteins are key in regulating the stability and translation of a significant number of mRNAs in the cell.
Such cognitions and thoughts might be key in their ability to regulate emotions, and not be overwhelmed by them, during stressful life events such as long periods of unemployment.
Previous studies have shown that ETS transcription factors may be key mediators in regulating PARP expression [ 15].
DNMTs may be key players in regulating histones and the entire epigenomic machinery, since DNA methylation events often precede histone modifications [ 67].
As mentioned earlier, μ- and κ-opioid receptors are key players in regulating pruritus in the central nervous system, but epidermal keratinocytes reportedly express these opioid receptors both in vitro and in vivo, 53 suggesting nalfurafine can exert its antipruritic activity through κ-opioid receptors in the epidermis.
Immune semaphorins are key players in regulating immune mediated inflammation.
Taken together, these results indicate that DREB2C and HsfA3 are key players in regulating the heat tolerance of Arabidopsis.
However, studies have demonstrated that the members of the Ras family of small GTP-binding proteins and their downstream effectors are key players in regulating integrin activation.
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