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Network analysis of the temporal expression profile indicated that transcription factors foxl1, wt1, nr5a1, nr6a1, and especially, hnf4a may be key coordinators of the homeostatic response to zinc depletion.
DNA-binding proteins was one of the largest molecular function groups among regulated genes, and bioinformatic analysis of the temporal gene expression profile indicated that transcription factors foxl1, wt1, nr5a1, nr6a1, and especially, hnf4a may be key coordinators of the homeostatic response to zinc depletion.
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These results confirm that microRNAs are key coordinators of the intracellular pathways that mediate experience-dependent changes in the brain.
Although they represent a minority of cells in the cortex, interneurons are key coordinators of intercellular communications and serve a crucial role in modulating neuronal output via the release of γ-aminobutyric acid (GABA) and neuropeptides (Baraban and Tallent 2004).
Our results suggest that HF biomarkers may be defined as key coordinators of intra- and inter-module communication.
Based on our analyses, HF biomarkers may be characterized as key coordinators of intra- and inter-module communication.
CTCF has been termed the "master weaver" of the genome, since this protein is a key coordinator of chromatin loop formation.
CTCF is a key coordinator of three-dimensional chromatin structure, allowing loop formation and specific chromatin compositions [ 2, 3].
The mTOR signaling pathway is a key coordinator of cell growth and cell proliferation in response to a variety of environmental conditions.
Therefore, it might be essential to identify and characterize the key coordinators of Atg7-mediated autophagy and other regulatory networks.
Our findings are supportive of similar scaffolding mechanisms at inhibitory synapses, and suggest that the GIT1/βPIX signaling pathway may represent a key coordinator of actin pathways at synapses.
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