Your English writing platform
Discover LudwigSuggestions(5)
Exact(52)
Residues proposed to be involved in substrate binding (Law et al. 2009) are shaded dark gray.
The inserted sub-domain is shown to be involved in substrate binding and dimerization.
Residues W82, E197, and A328 in the active site gorge have been reported to be involved in substrate activation.
For other members of this superfamily, the hemopexin-like domain has been described to be involved in substrate recognition.
By integration of homology modeling, residue coevolution and site-directed mutagenesis, we discover that four covarying amino acids including C393 constitute a dynamic domain that may be involved in substrate folding process for Bi.
The multiple sequence alignment of all experimentally confirmed CAR protein sequences revealed fingerprint sequences of residues which are likely to be involved in substrate and co-substrate binding and one of the three catalytic substeps, respectively.
Similar(8)
Four LysR-type transcriptional regulators were found within this locus, which could be involved in substrate-dependant regulation of metabolic pathways (Maddocks and Oyston 2008).
The modeled structure suggest also an additional highly conserved His residue (H43) that could be a part of the metal ion-binding site or be involved in substrate-binding.
Comparative genomic analysis identified several mutations in the putative promoters and within the coding region of genes which might be involved in substrates utilization (Table 2, 3).
Ancillary domains, some of which are involved in substrate recognition, are also depicted.
More importantly, PC1 is involved in substrate binding in both the access and binding phases.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com