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Hypotheses about how parahippocampal and hippocampal structures may be involved in spatial navigation tasks are implemented in a model of a virtual rat navigating through a virtual environment in search of a food reward.
When the researchers looked at the parts of the brain that were engaged when the subjects memorized, they found that the mental athletes were relying more heavily on regions known to be involved in spatial memory.
In response, the patient showed increased activation in the supplementary motor area (where voluntary motor responses are prepared for execution by the primary motor cortex) and the parahippocampal gyrus (an area of the medial temporal lobe known to be involved in spatial processing).
The findings showed that the conscious experience of where one's body is located arises from activity in brain areas involved in feelings of body ownership, as well as regions that contain cells known to be involved in spatial orientation, the researchers said.
In summary, according to the present results, the cerebellum seems to be involved in spatial learning and/or spatial orientation as well as in visuomotor [47] and oculomotor [48] coordination.
Moreover, the induction of IL-1β synthesis and c-Fos expression in the hippocampus in response to the spatial task was abolished in P2X7R−/− mice, suggesting that hippocampal IL-1β production may be involved in spatial memory performance.
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These structures are located on the inner surface of the temporal lobe and are involved in spatial memory and navigation.
Taken together, our experiments prove that the avian hippocampus is involved in spatial learning, but not in pattern discrimination tasks.
This finding provides electrophysiological confirmation that the human premotor cortex is involved in spatial attention and/or working memory.
These cells are found in the brain's hippocampal formation, a region that, in humans, is involved in spatial learning, autobiographical memories and knowledge of general facts about the world.
It appears that CTCF largely mediates the effects of curaxins on the 3D genome; however, it is still questionable whether other transcription factors that are involved in spatial genome organization contribute to the effect.
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