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A limitation in gene expression studies is that individual genes are assigned a specific function, but the gene may be involved in functional categories.
This type of position has been shown repeatedly to be involved in functional specialization and of use in engineering proteins to switch their function from one class to that of the other [ 8, 9, 13, 14].
Recently it was proposed that the C-termini of Hfq subunits in Hfq6 complexes could be involved in functional interactions with other Hfq hexamers and/or nucleic acids.
NSCS change the amino acid sequence of proteins and are therefore natural candidates to be involved in functional interactions, in contrast to combinations of NS that will provide an estimate of the background levels of genetic differences between populations.
To further identify the amino acid sites that might be involved in functional divergence of the CYP3 family in Actinopterygii, we compared the significant values of θI using a posteriori probability analysis, and a site with θI>0.9 was thought to be a potential type I site.
It has been shown to be involved in functional impairment of the BBB [ 47 ].
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In order to test out whether the N-Cadherin was involved in functional structures, we analysed the distribution of the actin microfilaments by Phalloidin staining.
Because quite a number of lncRNAs arise from protein-coding regions, it is conceivable that they are involved in functional roles complementing to that of the parent protein-coding gene.
Among them, nine were encoded by significantly differentially-expressed genes, such as MAPK1 or PDIA3, which are involved in functional pathways such as natural killer cell mediated cytotoxicity or MAPK signalling.
Other proteins whose interacting partners were encoded by more than 15 significantly differentially-expressed genes were TP53, NR3C1, SMAD2, CASP3, ESR1, RB1 and YWHAG (Annex S1 shows complete list), which are involved in functional processes such as apoptosis or cell cycle.
This fragment, according to the authors, is involved in functional adaptations of cardiac muscle [ 24].
More suggestions(17)
be involved in organizational
be involved in operational
be included in functional
be involved in practices
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be involved in professional
be involved in practical
be incorporated in functional
be organized in functional
be involved in charitable
be shown in functional
be detected in functional
be 'explained in functional
be made in functional
be ignored in functional
be linked in functional
be enriched in functional
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