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This lack of ubiquitous protein densities could be attributed to the low number of synaptic proteins that are expected to be involved in docking and exocytosis (van den Bogaart and Jahn, 2011); proteins could also be overlapping with the interface in projection and be masked by the high-contrast lipids.
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Syt VII is involved in docking and fusion of vesicles with the plasma membrane where it participates in formation of the SNARE complex [75].
Three subunits at the stromal site of PSI are involved in docking and reducing ferredoxin I: PsaC (with [4Fe 4S] clusters FA and FB), PsaD, and PsaE.
CUTI-1 may be involved in the docking or fusion of vesicles either within the epithelia or to the epithelial membrane.
Such fusions have been observed between the mitochondria and ER [ 48], where it was suggested that vesicle associated membrane protein 1 (VAMP-1) might be involved in the docking of mitochondria to target membranes [ 49].
In neuroendocrine cells, SNARE chaperones, such as MUNC18 family, small GTPases like RAB3 and calcium-sensing family of synaptotagmins, as well as SNAREs themselves are thought to be involved in those docking and 'priming' steps (Weimer & Jorgensen, 2003; Wu et al, 2012).
Differentially modified residues from the experimental results were forced to be involved in an interdomain interaction during the docking process.
The protein residues with chemical shift changes > 0.075 as well as those that disappeared upon adding ligand were deemed to be involved in binding for the purposes of docking experiments.
I grew up down the street from a man who worked on the docks, who had to be involved in some way with the Mafia.
In addition to residues identified by NMR, docking simulations suggested that additional residues may possibly be involved in ligand binding.
Docking studies allowed us to provide insight into the molecular interactions between QS modulators and LasRLBD that may be involved in the differential SERS fingerprints obtained.
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CEO of Professional Science Editing for Scientists @ prosciediting.com