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Since BDNF plays a significant role in the above mentioned processes, it would be intriguing to study the regulation of BDNF by EGR factors.
It will be intriguing to study how these cytoplasmic functions of Rb relate to its role as a transcriptional regulator in the nucleus and how Rb is distributed between different cellular compartments.
It would be intriguing to study whether the frog gene is specifically expressed in the nervous system and whether the transcripts are localized in the nucleus; these are the two criteria used to define the Gomafu lncRNA family.
It would be intriguing to study effects of RBX on endothelial insulin sensitivity in the clinic to complement existing data solely focusing on the endothelial dysfunction due to impaired acetylcholine-dependent vasodilation [ 7- 9].
Because the increase in total bacterial load following exposure to DSS could either be a cause or effect of the mucosecretory phenotype, it will be intriguing to study the compositional changes to the microbiota of inflamed larval zebrafish with molecular techniques.
Although Celf3 knockout mice do not exhibit obvious neuronal phenotypes (Dev 2006), it would be intriguing to study the expression of Gomafu in the Celf3 knockout mice or in neurons depleted of all of the neuronal Celf family RNA-binding proteins.
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Since the ICAM-5 cytoplasmic domain perturbs GluN1 and α-actinin binding, it was intriguing to study its effect on α-actinin distribution.
It would have been intriguing to study the correlations, if any between the processes of genome reshuffling and the evolution of gene orientation.
Although the mechanism by which VASH1 regulates EC survival is beyond the scope of this study, it is intriguing to examine the function of VASH1's GRN children in the anticipation that this may suggest how VASH1 acts.
Although our findings are derived from an observational study, it is intriguing to consider that uric acid might play a pathogenic role in the development of early GFR loss in type 1 diabetes.
It will be intriguing to extend these analyses to the study of more distant genetic control of gene expression at the single-cell level (that is, single-cell trans-eQTLs) and to investigate the functional relevance of scQTLs on whole-body phenotypes in human and animal models.
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