Human whole-genome sequencing with next-generation sequencing usually produces hundreds of gigabases, thus WGS mapping or assembly tools generally requires large memory such that it is intractable to use such tools for specific genotyping.
Some patients may be intractable to the therapies recommended by national guidelines, and following the need of clinicians the word "intractable" has been defined by Goadsby et al. entitled "Towards a Definition of Intractable Headache for Use in Clinical Practice and Trials" [10].
The B97-D/TZVP case represents a favorable example with small mean errors and relatively tight error distributions (see Table 1 for other examples), but it would be computationally intractable to use it to study hundreds or thousands of decoys for a system of the size of ubiquitin.
On the other hand, higher proportions of people with conditions that are complex, involve pain management, and whose effects may be intractable using conventional medicines report seeking assistance from CAM practitioners.
The resulting equations for the posterior pdfs are intractable so we use MCMC methods to sample from the posterior distributions.
Instead of building a complete Bayesian graph, which is intractable, HNB is used to construct the dependencies between attributes A i with a hidden parent A hp i.
Exact learning is intractable, hence, we use an approximate technique called contrastive divergence (CD) algorithm [26,39].
One species, H. mana, proved to be intractable with this primer combination and was amplified using a novel primer, C1-J-1580, as the forward primer.
