The aligned sequences were interrogated at each amino acid position, using the Shannon entropy of physiochemical property method (Capra and Singh, 2007; Mirny and Shakhnovich, 1999), and scores were plotted onto the HB3var03 CIDRα1 structure.
A lawyer for a Brooklyn man charged with assisting in an aborted bomb plot accused the government yesterday of timing his client's arrest to coincide with a court holiday so that he could then be interrogated at length before being given a lawyer or taken before a judge.
The methylation status of a tissue sample can be interrogated at the individual CpG level in two chief ways [ 14].
Multiple driver mutations were identified in several cases, reinforcing the idea that multiple genes need to be interrogated at once in genomically complex tumors such as gastric adenocarcinomas.
Therefore, we propose that CSC-associated populations should be interrogated at the genetic level including the ploidy profile compared with the tumour bulk.
By using an inducible system, the timing and the proportion of cells that undergo genetic recombination can be refined, such that the contribution of specific cells to tissues at defined developmental time points can be interrogated at clonal densities.
While this method is robust, it is subject to amplification biases and considered very laborious, allowing only for a limited number of sites to be interrogated at a time.
The recently developed RNA interference (RNAi) technology has created an unprecedented opportunity which allows the function of individual genes in whole organisms or cell lines to be interrogated at genome-wide scale.
We are likely to see improved epidemiological data for a variety of conditions in critical care with the UK, France, Australia and New Zealand all producing high quality, validated national audits of critical care activity which may be interrogated at the national or local level.
The VNB device was interrogated at the time of each study visit to ensure appropriate duration of use, and proper function, over the 2-week interval preceding each study.
